Budesonide Nasal Spray: The One And Only Pregnancy Safe Nasal Corticosteroid

Contents:
01. Description
02. Mechanism of action
03. Indication
04. Dosage and Administration
05. Special Features
06.Available Brands


Description:
Budesonide is a synthetic glucocorticoid steroidhaving potent glucocoticoid activity and weak mineralocorticoid activity.It has approximately a 200-fold higher affinity for the glucocorticoid receptor and a 100-fold  higher  topical anti inflammatory potency than cortisol. 

Mechanism of Action:
Budesonide inhibits inflammatory mediators release in nasal mucosa.The inflammatory mediators are-

•  Histamine
• Tryptase
• Prostaglandins
• Eosinophils
• Basophils

Budesonide also inhibits-

• Venule dialation
• Nasal swelling

                            Thus Budesonide provides  Anti inflammatory and decongestant effect.

Indications:

1. Rhinitis
2. Asthma with persistant rhinitis
3. Rhinosinusitis

Dosage and Administration:

From the 6 years of age: 1 spray for each nostril (Maximum 2 sprays for each nostrils)

Special Features:

01. US FDA pregnancy category B
02. Australian Drug Evaluation Committee  pregnancy category A
03. Can be used from the 6 years of age
04. Superior than Beclomethasone
05.Recommended by National Asthma Council Australia

Available Brand:
01. Rhinocort-AstraZeneca,UK
02.Budicort- Incepta Pharmaceuticals Lt. BD
03.Pulmicort Nasal spray- Opsonin Pharma Ltd.
04.Butacort-Pacific Pharmaceuticals

Rhinocort Nasal Spray

Budicort Nasal Spray

Rhinocort

Butacort Nasal Spray

Pulmicort Nasal Spray